Bobby and Becca Warren are enjoying college life when a mysterious disease ravages the country. With chaos ensuing, they head for home to join their family, but when they arrive they discover their home has been burned and find the graves of their mother and youngest brother in the backyard.
With scavengers swarming over the neighborhood, the siblings decide to search for their father using clues he has left for them, but before they can find him they are captured by a local militia. Caught between a psychotic killer and an advancing foreign army with no chance to escape, their only hope rests with their father, who doesn't even know they are alive.
