Meet Henry and Winthrop: friends since forever, manga and anime fans, and dead sick of the daily grind. Henry's girlfriend of four years just walked out on him after a dumb argument about salad dressing and "Cowboy Bebop". Winthrop's burned out on his comic store -- paradise when you're nineteen, but maybe not when you're thirty-six.
What's left but to rent a car and a hotel room, gather some friends together, get dressed up as video-game characters and head south to drink in the biggest fan convention this side of the Missouri? That's the plan for the four-day weekend, anyway -- but every time they've tried to "get away from it all", they've wound up taking most of it with them.
And life has a funny way of happening when you've got plans, or even just a schedule. Into both of their lives comes crashing Diane, who's never seen an episode of "Dragonball Z" in her life and neither reads nor can spell Shonen Jump. A "mundane". And as it turns out, she might need someone like them just as much as they need someone like her.